WEBREVIEW

Antioxidant activity of Imino-Hesperidin derivatives

Belboukhari N., Cheikh N., Cheriti A., Fandougouma O. — 2015-07-07T09:34:41Z

DMF solution of imino-Hesperidin derivatives was screened for its antioxidant activity based on their capacity to scavenge the free β-carotene radical after exposure to a UV lamp at 254 nm. In the first time, we have synthesized seven new compounds derived from Hesperidin 1 based on condensation reactions and nucleophile additions simple and easy to carry. Hesperidin 1 which is a natural molecule extracted in the laboratory (LPOS) from orange peel (genre Citrus sp.), which is the best known (...)

- Numéro1 / Hesperidin, Citrus sp., antioxidant, β -carotene

In vitro effect of Hesperidin & Hesperitin on calcium oxalate Crystallization : The Chiral Impact

Belboukhari N., Cheriti A., Lahmer N. , Naas A. , Sekkoum K. — 2015-07-07T09:34:23Z

Hesperidin, an abundant bioflavonoid in citrus fruits, has been reported to possess a wide range of pharmacological properties. In this study, the antilithiasic activity of hesperidin a glycoside flavanone extracted from leaves peel of three different citrus species, (C. reticulata, C. clementina, C. sinensis), this activity may be explained by interaction of two enantiomers or diastereomers of hesperidin and (...)

- Numéro1 / Hesperidin, Hesperitin, flavanone glycoside, orange peels, calcium oxalate, antilithiasic activity

Etude de l'effet des huiles e ssentielles brutes foliaires de Colocynthis vulgaris (L.) Schrad (Cucurbitaceae) sur l' activité cholinestérasique chez les imagos de Schistocerca gregaria (Forskål, 1775)

2015-07-07T09:19:07Z

Le présent travail porte sur l'étude de l'effet de la toxicité sur l'activité cholinestérasique et quelques paramètres physiologiques chez des individus mâles et femelles de Schistocerca gregaria élevé en laboratoire et exposé aux huiles essentielles brutes des feuilles de Colocynthis vulgaris. Les manifestations d'intolérance générale à cet extrait apparaissent vers 30 à 60 minutes après l'exposition, l'activité cholinésterasique montre une diminution par rapport aux individus témoins, elle est de 8,08±2,65 nanomole/mn/ml chez les mâles, et de 16,34±1,15 nanomole/mn/ml chez les femelles de Schistocerca gregaria traités par l'extrait d'huiles essentielles de C. vulgaris. Pour les lots des individus traités, le taux de protéines laisse apparaître une différence entre les femelles et les mâles. Il augmente chez les individus mâles pour atteindre 46,11±16,17 μg/ml alors qu'il est 35±13,22 μg/ml chez les individus femelles. Toutefois, l'activité spécifique chez les individus traités diminue chez les mâles (0,19±0,04 nanomole /min /mg), mais pour les femelles traitées semble stable avec 0,49±0,26 nanomole /min /mg. De même, les individus de Schistocerca gregaria exposés à l'extrait d'huiles essentielles brutes foliaires, laissent apparaître des perturbations au niveau des réponses neurochimiques et comportementales, d'où une toxicité accrue de cet extrait de C. vulgaris.

Age-related macular degeneration (AMD) is a...

Ayesha F., Sara F., Sobia N. — 2015-07-06T12:50:22Z

Age-related macular degeneration (AMD) is a condition characterized, in the early stages, by slow development and progression, absence of symptoms over a number of years, and extensive retinal deposits called drusen, often associated with pigmentary abnormalities (early AMD).There is strong and consistent evidence that increasing age, family history, obesity/high body mass index, and cataract surgery are associated with late AMD.
Smoking is the strongest and most consistently found (...)

- Numéro1 / Ranibizumab, age-related macular degeneration, smoking, vascular endothelial growth factor, bevacizumab, pegaptanib

Acacia Arabica plant is well known in the...

Ghiaba Z., Moulay Y., Saidi M. — 2015-07-06T12:50:20Z

Acacia Arabica plant is well known in the region of North African Sahara for its efficiency in the traditional treatment of several diseases such as diarrhoea, eczema, tonsillitis and conjunctivitis. This work was aimed to determine the total phenolic content and antioxid ant activity of methanol:water (8:2) and acetone:water (7:3) extracts of barks of Acacia Arabica growing in Tamanrasset (Algeria). Total phenolic contents of the extracts were determined by the Folin-Ciocalteu method and (...)

- Numéro1 / DPPH, antioxidant activity, Acacia arabica, total phenolic, hosphomolybdenum assay, RPA

A new analytical method was developed for the...

Daghbouche Y., Bouzidi N. , El hattab M. , Seridi H. — 2015-07-06T12:50:17Z

A new analytical method was developed for the determination of free sterols in the extracts of the red alga Asparagopsis armata and the brown one Cystoseira sedoides by using FTIR spectrometry. Sterols samples were globally refered to cholesterol content because it is the major sterol contained in red algae [1] and to fucosterol because it is the principal one contained in brown ones [2]. The method involves the use of cholesterol as reference standard in the case of red alga and a correction factor of 1.259 ±0.003, which represents the ratio between the slopes of calibration lines obtained from fucosterol and cholesterol in the case of brown alga. To isolate the sterols, the lipidic extract of the algae were heated in methanol and diluted with water and then preconcentrated on DSC-18 solid phase cartridges and eluted with 1 mL dichloromethane stabilized with β-amylene. The determination of free sterols by Fourier transform infrared spectrometry was carried out by considering the specific band of cholesterol at 1047 cm-1 corrected with a baseline established between 1060 and 1014 cm-1. The sterols content were obtained by the external calibration. The concentrations obtained were 1.9 ± 0.5 % and 1.5 ± 0.4 % in Asparagopsis armata and Cystoseira sedoides, respectively.

Fusarium oxysporum f. sp. albedinis (Foa) is...

Boulenouar N., Cheriti A., Marouf A. — 2015-07-06T12:50:06Z

Fusarium oxysporum f. sp. albedinis (Foa) is the causal agent of a lethal disease of date palm “Phoenix dactylifera L.” called Bayoud. The antifungal test against Foa was evaluated using direct bioautography for extracts from four medicinal and/or poisonous plants (Acacia raddiana, Asteriscus graveolens (Forsk.), Citrullus colocynhis (L.) Schrad, Pergularia to mentosa). The choice of extracts was based on activity against Foa using disc diffusion techniques and relative virulence. The most effective extracts (detected inhibition and relative virulence decreased below 50%) were chosen for direct bioautography test. Direct bioautography has a great importance based on effectiveness. Extracts from Acacia raddiana showed no effect on chromatograms. The best results were represented by ethyl acetate extract of Citrullus colocynthis fruits (7.75 +and- 1.06 mm) and ethyle acetate extract of Asteriscus graveolens stems (7.00+and -1.41 mm). The efficiency of some species especially Citrullus colocynthis indicates the presence of highly sensitive targets in foa, which can be exploited for the development of efficient treatment against Bayoud.

The Coumarin from Euphorbia guyoniana Boissier and Reuter

B.Legseir , C.Moral-Salmi , C.Vigor, J.Vercauteren , Julia A., O.Smara — 2015-02-03T09:44:12Z

Esculetin is a phenolic compound that is found in various natural plant products and induces apoptosis in several types of human cancer cells. However, the underlying mechanisms of its action are not completely understood. In the present work a phytochemical study of ethyl acetate extracted from the aerial parts of Euphorbia guyoniana plant endemic of Algeria, led to the isolation of a compound (esculetin). The purification of this compound was by column chromatography and TLC. The (...)

- Numéro1 / Euphorbiaceae, Euphorbia, guyoniana, coumarin and esculetin

Development of extraction and analysis of polyphenols of Mesembryanthemum edule L.

C. Aouf, D. El Abed, F. Veran, H. Fulcrand , J.P. Mazauric, M. Chenni — 2015-02-03T09:33:02Z

Mesembryanthemum edule (Aizoaceae family) is an edible halophyte widely used as a food ingredient and in traditional medicine. This study was intended to characterize the phenolic compounds of M. edule fresh and stone stems. The approach consisted to establish the phenolic composition through LC-DAD-ESI/MS consisted of an Acquity UPLC (Waters, Milford, MA) coupled with DAD and a Brucker Daltonics Ion trap mass spectrophotometer. The UPLC analysis revealed that the main phenolic compounds (...)

- Numéro1 / Aizoaceae, Mesembryanthemum edule, Phenolic compounds, LC-DAD-ESI/MS